From Rigpa Wiki
མཁའ་འགྲོ་མ་, khandroma; Wyl. mkha' 'gro ma) — a female embodiment of enlightened energy. ‘Khandro’ (མཁའ་འགྲོ་) literally means ‘sky-goer’, indicating one who traverses the 'sky' of the expanse of wisdom. Female lamas and the spiritual wives of male lamas often have the epithet 'khandro'.